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Journal of Big Data
Fig. 1 | Journal of Big Data

Fig. 1

From: Conventional dendritic cell 2 links the genetic causal association from allergic asthma to COVID-19: a Mendelian randomization and transcriptomic study

Fig. 1

Study design overview. Genomic and transcriptomic data of COVID-19 and allergic diseases were collected from public platforms. The causal correlations between allergy and COVID-19 were detected using the Mendelian randomization (MR) analysis, and blood parameters were used as mediating variables. Based on MR results, the study further applied bulk-tissue transcriptome, single-cell transcriptome, and molecular docking analyses to explore the potential cellular and molecular mechanism that bridges the allergic asthma (AA) and COVID-19

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