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Fig. 7 | Journal of Big Data

Fig. 7

From: Liquid biopsy-based identification of prognostic and immunotherapeutically relevant gene signatures in lower grade glioma

Fig. 7

Construction of RRG-related RiskScore. a, b Kaplan–Meier curves for OS showing the difference in survival between high-RiskScore group and low-RiskScore group in the TCGA (a) and CGGA (b) cohorts (log-rank test, p < 0.0001). High-RiskScore group is indicated in red line and low-RiskScore group in blue. c The predictive value of RiskScore in patients among the TCGA cohort (AUC:0.89, 083, and 0.71; 1, 3, and 5-years overall survival). d, e Multivariate Cox regression model analysis, which included the factors of RiskScore, age, gender, IDH1 status, grade, histology and patient outcomes in the TCGA (d) and CGGA (e) cohorts. The length of the horizontal line represents the 95% confidence interval (CI) for each group. The vertical dotted line represents the hazard ratio (HR) of all patients shown by the forest plot. *P < 0.05, **P < 0.01, ***P < 0.001

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