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Journal of Big Data
Fig. 4 | Journal of Big Data

Fig. 4

From: Liquid biopsy-based identification of prognostic and immunotherapeutically relevant gene signatures in lower grade glioma

Fig. 4

Immune-related features of response-related clusters. a The relative abundance of each circulating immune cells in three response-related clusters. The upper and lower ends of the boxes represented interquartile range of values. The lines in the boxes represented median value, and dots showed outliers. b EMT-relevant genes (CLDN7, CLDN4, CDH1, VIM, ZEB1, and ZEB2) expressed in three response-related clusters. c Immune-checkpoint-relevant genes (CD274, CTLA4, HAVCR2, LAG3, PDCD1, PDCD1LG2, and TIGIT) expressed in three response-related clusters. d Immune activation-relevant genes (CD8A, CXCL10, CXCL9, GZMA, GZMB, IFNG, and TBX21) expressed in three response-related clusters. Within each cluster, the upper and lower ends of the boxes represented interquartile range of values. The lines in the boxes represented median value, and black dots showed outliers. e Enrichment plots showing the relatively significantly enriched pathways in clusters 1, 2 and 3. Different pathways are indicated by different colors in each enrichment plot

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