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Journal of Big Data
Fig. 10 | Journal of Big Data

Fig. 10

From: Liquid biopsy-based identification of prognostic and immunotherapeutically relevant gene signatures in lower grade glioma

Fig. 10

The RRG-related RiskScore predicts immunotherapeutic benefits. a, b Kaplan–Meier curves for OS (a) and PFS (b) showing the difference in survival between high-RiskScore group and low-RiskScore group (log-rank test, p < 0.0001). High-RiskScore group is indicated in red line and low-RiskScore group in blue. c Rate of clinical response (Response and Non-response) to anti-PD-1 immunotherapy in high or low RiskScore groups. d Heatmap of 28 previously reported immune cells infiltration in high-RiskScore group and low-RiskScore group. e Boxplots of the relationship between RRG-related RiskScore and 28 immune cell subpopulations. The upper and lower ends of the boxes represented interquartile range of values. The lines in the boxes represented median value, and black dots showed outliers. *P < 0.05, **P < 0.01, ***P < 0.001

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