Fig. 4

Correlation between TME infiltration cells and ferroptosis regulators and the roles of FBXW7 in activation of dendritic cells. A Difference in gene expression between FBXW7 mut and wt. B The correlation between TME infiltration cells and ferroptosis regulators. C Difference in the abundance of TME infiltrating cells. D Difference in expression of HLA genes and ICPs. E Difference in immuneScore. F Differences in immune-activated pathways. G, H Survival analyses for patients in TCGA (G) and anti-PD-L1 (H) immunotherapy cohort (*p < 0.05; **p < 0.01; ***p < 0.001)