Skip to main content

Table 3 Effects of varying feature sizes on all the Test-3 dataset when k-mer size is 3 for the forward feature set

From: A novel feature extraction method based on highly expressed SNPs for tissue-specific gene prediction

Tissue

Feature size

[6, 7, 8]

[7, 8, 9]

[8, 9, 10]

[9, 10, 11]

[10, 11, 12]

Acc

F1

Acc

F1

Acc

F1

Acc

F1

Acc

F1

Adipose subcutaneous

0.84

0.80

0.93

0.91

0.97

0.97

0.99

0.99

0.99

0.99

Adipose visceral omentum

0.87

0.84

0.95

0.94

0.98

0.97

0.99

0.99

0.99

0.99

Adrenal gland

0.91

0.89

0.96

0.95

0.98

0.98

0.99

0.99

1.00

1.00

Artery aorta

0.86

0.83

0.95

0.93

0.98

0.97

0.99

0.98

0.99

0.99

Artery coronary

0.94

0.92

0.98

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Artery tibial

0.84

0.81

0.93

0.92

0.97

0.96

0.99

0.98

0.99

0.99

Brain amygdala

0.96

0.96

0.98

0.98

0.99

0.99

1.00

1.00

1.00

1.00

Brain anterior cingulate cortex

0.94

0.93

0.97

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Brain caudate basal ganglia

0.92

0.90

0.97

0.96

0.99

0.98

0.99

0.99

1.00

1.00

Brain cerebellar hemisphere

0.90

0.88

0.96

0.95

0.98

0.98

0.99

0.99

1.00

0.99

Brain cerebellum

0.88

0.85

0.96

0.95

0.98

0.98

0.99

0.99

1.00

0.99

Brain cortex

0.91

0.89

0.97

0.96

0.99

0.98

0.99

0.99

1.00

1.00

Brain frontal cortex

0.93

0.91

0.97

0.96

0.99

0.98

0.99

0.99

1.00

1.00

Brain hippocampus

0.94

0.93

0.98

0.98

0.99

0.99

1.00

0.99

1.00

1.00

Brain hypothalamus

0.95

0.93

0.98

0.97

0.99

0.99

1.00

1.00

1.00

1.00

Brain nucleus accumbens basal ganglia

0.92

0.90

0.97

0.96

0.99

0.99

0.99

0.99

1.00

1.00

Brain putamen basal ganglia

0.93

0.91

0.98

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Brain spinal cord cervical

0.96

0.95

0.98

0.98

0.99

0.99

1.00

1.00

1.00

1.00

Brain substantia nigra

0.97

0.96

0.99

0.98

0.99

0.99

1.00

1.00

1.00

1.00

Breast mammary

0.89

0.86

0.95

0.94

0.98

0.98

0.99

0.99

1.00

0.99

Cells cultured fibroblasts

0.84

0.81

0.93

0.92

0.97

0.97

0.99

0.98

0.99

0.99

Cells EBV transformed lymphocytes

0.94

0.93

0.98

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Colon sigmoid

0.89

0.86

0.96

0.94

0.98

0.97

0.99

0.99

0.99

0.99

Colon transverse

0.88

0.85

0.95

0.93

0.98

0.97

0.99

0.99

1.00

0.99

Esophagus gastroesophageal junction

0.89

0.86

0.96

0.95

0.98

0.98

0.99

0.99

0.99

0.99

Esophagus mucosa

0.85

0.82

0.94

0.92

0.97

0.97

0.99

0.98

0.99

0.99

Esophagus muscularis

0.85

0.82

0.94

0.93

0.98

0.97

0.99

0.98

0.99

0.99

Heart atrial appendage

0.88

0.86

0.95

0.94

0.98

0.97

0.99

0.99

1.00

0.99

Heart left ventricle

0.91

0.88

0.96

0.95

0.98

0.98

0.99

0.99

1.00

1.00

Kidney cortex

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

Liver

0.94

0.92

0.97

0.97

0.99

0.98

1.00

1.00

1.00

1.00

Lung

0.86

0.82

0.94

0.93

0.98

0.97

0.99

0.98

0.99

0.99

Minor salivary gland

0.95

0.94

0.98

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Muscle skeletal

0.86

0.82

0.94

0.92

0.98

0.97

0.99

0.99

0.99

0.99

Nerve tibial

0.82

0.78

0.92

0.90

0.97

0.96

0.99

0.98

0.99

0.99

Ovary

0.94

0.93

0.98

0.97

0.99

0.99

1.00

1.00

1.00

1.00

Pancreas

0.90

0.87

0.96

0.95

0.98

0.98

0.99

0.99

1.00

0.99

Pituitary

0.91

0.88

0.96

0.95

0.99

0.98

0.99

0.99

1.00

1.00

Prostate

0.93

0.91

0.97

0.97

0.99

0.98

1.00

0.99

1.00

1.00

Skin not sun exposed suprapubic

0.84

0.80

0.93

0.92

0.97

0.96

0.99

0.98

0.99

0.99

Skin sun exposed lower leg

0.84

0.80

0.93

0.91

0.97

0.96

0.99

0.98

0.99

0.99

Small intestine terminal ileum

0.94

0.92

0.98

0.97

0.99

0.99

1.00

0.99

1.00

1.00

Spleen

0.89

0.86

0.95

0.94

0.98

0.98

0.99

0.99

1.00

0.99

Stomach

0.91

0.88

0.96

0.95

0.98

0.98

0.99

0.99

1.00

1.00

Testis

0.83

0.79

0.93

0.91

0.97

0.96

0.99

0.98

0.99

0.99

Thyroid

0.82

0.78

0.92

0.90

0.97

0.96

0.98

0.98

0.99

0.99

Uterus

0.96

0.95

0.99

0.98

0.99

0.99

1.00

1.00

1.00

1.00

Vagina

0.97

0.96

0.99

0.98

0.99

0.99

1.00

1.00

1.00

1.00

Whole blood

0.86

0.83

0.94

0.93

0.98

0.97

0.99

0.99

0.99

0.99

MEAN

0.90

0.88

0.96

0.95

0.98

0.98

0.99

0.99

1.00

0.99

STDEV

0.05

0.06

0.02

0.02

0.01

0.01

0.00

0.00

0.00

0.00

MIN

0.82

0.78

0.92

0.90

0.97

0.96

0.98

0.98

0.99

0.99

MAX

0.99

0.99

1.00

1.00

1.00

1.00

1.00

1.00

1.00

1.00

  1. Accuracy indicated by Acc and F1-Score indicated by F1