Table 7 The annotations of transcription factors regulating the harvested genes from the feature selection step

Pathways in cancer

1.2063332677701377E−19

3.715506464732024E−17

STAT5A;STAT5B;TCF7L2;JUN;SPI1;STAT1;LEF1;STAT3;MITF;HIF1A;ESR1;RELA;NFKB1;AR;RXRA;SP1;E2F1;STAT4;EP300;CTNNB1;TP53

Wnt signaling pathway

9.705297353623653E−9

1.5732797815347815E−7

TCF7L2;JUN;LEF1;EP300;NFATC2;CTNNB1;NFATC1;TP53

Non-small cell lung cancer

2.334429995619187E−8

3.126106255003085E−7

STAT5A;STAT5B;RXRA;STAT3;E2F1;TP53

TNF signaling pathway

5.026455978790371E−7

4.553377769021866E−6

ATF2;JUN;CREB1;IRF1;RELA;NFKB1

JAK-STAT signaling pathway

4.820060593301115E−6

3.620923567650594E−5

STAT5A;STAT5B;STAT1;STAT3;STAT4;EP300

Small cell lung cancer

5.15158695877854E−6

3.6899739146599775E−5

RXRA;E2F1;TP53;RELA;NFKB1

HIF-1 signaling pathway

7.356942182113052E−6

5.035418204646267E−5

STAT3;EP300;HIF1A;RELA;NFKB1

cAMP signaling pathway

2.2332816777813463E−5

1.4037770546054178E−4

JUN;CREB1;EP300;NFATC1;RELA;NFKB1

Apoptosis

4.156130787036355E−5

2.3274332407403588E−4

JUN;PARP1;TP53;RELA;NFKB1

Adherens junction

4.260972052484695E−5

2.3435346288665825E−4

TCF7L2;LEF1;EP300;CTNNB1

MAPK signaling pathway

1.39454465445684E−4

7.158662559545113E−4

ATF2;JUN;NFATC1;TP53;RELA;NFKB1

Toll-like receptor signaling pathway

1.786661621004991E−4

8.59830905108652E−4

JUN;STAT1;RELA;NFKB1

PI3K-Akt signaling pathway

3.7197722896986754E−4

0.0016604200945321624

ATF2;CREB1;RXRA;TP53;RELA;NFKB1

cGMP-PKG signaling pathway

0.0010478054962433662

0.0042463696426704835

ATF2;CREB1;NFATC2;NFATC1

ErbB signaling pathway

0.0015715511019872403

0.006205612043744487

STAT5A;STAT5B;JUN

NF-kappa B signaling pathway

0.002160916108972604

0.008116611726384903

PARP1;RELA;NFKB1

Sphingolipid signaling pathway

0.004084635694037895

0.014800797573690256

TP53;RELA;NFKB1

Cell cycle

0.004582612813265843

0.01641214821495209

E2F1;EP300;TP53

FoxO signaling pathway

0.005453058494504465

0.01930508064721121

STAT3;EP300;SIRT1

Hippo signaling pathway

0.009248140092633821

0.03130139723660678

TCF7L2;LEF1;CTNNB1