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Table 3 Prediction of the large-joint-dominant patients with estimated vectors from target patients stratified by medication

From: Joint index vector: a novel assessment measure for stratified medicine in patients with rheumatoid arthritis

Target patients in 2015 (number of patients) PPV (%) NPV (%) LR
All patients (10,118) 58.7 85.1 5.9
MTX users (6254) 60.8 85.9 7.2
bDMARD users (2399) 67.9 82.3 7.4
MTX and bDMARD users (1436) 68.4 84.0 8.6
  1. Transformation matrices were derived from the patients in 2013 and 2014 with concordant medication of target patients
  2. PPV positive predictive value, NPV negative predictive value, LR positive likelihood ratio = sensitivity/(1 − specificity), MTX methotrexate