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Journal of Big Data
Fig. 7 | Journal of Big Data

Fig. 7

From: Integration of transcriptomic analysis and multiple machine learning approaches identifies NAFLD progression-specific hub genes to reveal distinct genomic patterns and actionable targets

Fig. 7

COL1A2 significantly correlates with EMT and angiogenesis in pan-cancer. (a) Correlation landscape of COL1A2 expression and ten cancer hallmarks including EMT, angiogenesis, apoptosis, inflammation, hypoxia, glycolysis, cell cycle progression (CCP), senescence, DNA repair and oxidative phosphorylation in pan-cancer. (b & c) Among all the cancer hallmarks, COL1A2 mostly correlated with EMT and angiogenesis in 32 solid malignancies (EMT: r = 0.86, p < 2.2e-16; Angiogenesis: r = 0.73, p < 2.2e-16) in the overall TCGA pan-cancer cohort. (d & e) COL1A2 exhibits significantly positive correlations with EMT and angiogenesis in individual cancer type

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