Fig. 5
From: Dissecting tumor antigens and immune subtypes for mRNA vaccine development in breast cancer
Identification of ISs in BRCA. a Tracking plot showing the stability of classification with subtype numbers. b Scree plot showing the relative change in the area under cumulative distribution function (CDF) curve with subtype numbers. c CDF plot showing the CDF with different subtype numbers. d Sample clustering heatmap with 2 divisions of the meta-BRCA cohort. (e) Kaplan‒Meier curve with log-rank test showing OS of ISs in the meta-BRCA cohort. f Kaplan‒Meier curve with log-rank test showing RFS of ISs in the METABRIC cohort. g Association of ISs with pathological M, T, N, S stage in the TCGA-BRCA cohort. NA not applicable, * p < 0.05, ** p < 0.01