Fig. 4

OTU feature selection results by Age Subrgoup. A The heat map depicts the relative abundance of the 57 most important bacterial microbiota (OTUs) for asthma diagnosis identified using the machine learning approach. The colors depict each OTU’s relative genera abundance among the tested subjects, grouped by age and ashtma diagnosis. B The figure depicts the Kruskual Wallis analysis of significant differential abundance of the 57 most important bacterial microbiota (OTUs) identified using the machine learning approach. The boxplots depict the relative phyla abundance of the selected OTUs among the tested subjects, grouped by age and ashtma diagnosis. Significant differential abundance can be observed among these phyla, as indicated by the adjusted p-values